SCHEMBL28415484

SCHEMBL28415484

CO[Si](CCCCNC(=O)Nc1ccccc1)(OC)OC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.68
EPHX1 P07099 4/20 0.64
ALDH1A1 P00352 4/20 0.64
HTT P42858 1/20 0.64
KDM4E B2RXH2 2/20 0.57
HDAC1 Q13547 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
FPR2 P25090 1/20 0.57
KMT2A Q03164 3/20 0.56
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
MARS1 P56192 1/20 0.52
CDK2 P24941 1/20 0.51
FLT4 P35916 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
CASR P41180 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17133246 0.95 LMNA (0.65) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL17133268 0.87 LMNA (0.56) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL28420696 0.86 EPHX1 (0.65) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL17133241 0.82 LMNA (0.63) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL17030472 0.82 KEAP1 (0.54) LMNAALDH1A1KDM4EKMT2ARAB9A
SCHEMBL19420655 0.82 EPHX1 (0.83) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL9547553 0.82 EPHX1 (0.83) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL17133269 0.82 LMNA (0.50) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL23583705 0.81 SAE1 (0.57) LMNAEPHX1ALDH1A1HTTKDM4E
SCHEMBL6280635 0.81 EPHX1 (0.62) LMNAEPHX1ALDH1A1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111373325-B Silicone resin composition, cured film, and display device 东丽株式会社 2023-10-17 CN disclosed
CN-111373325-A Silicone resin composition, cured film, and display device 东丽株式会社 2020-07-03 CN disclosed