Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 18/20 | 0.58 |
| ▸ | EP300 | Q09472 | 4/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413189 | 0.90 | CREBBP (0.58) | CREBBPEP300BRD2BRD3CLK2 | |
| SCHEMBL28415713 | 0.90 | CREBBP (0.46) | CREBBPEP300BRD2BRD3EPHB3 | |
| SCHEMBL28422569 | 0.89 | CREBBP (0.72) | CREBBPEP300BRD2BRD3EPHB3 | |
| SCHEMBL28417785 | 0.88 | CREBBP (0.44) | CREBBPEP300BRD2BRD3EPHB3 | |
| SCHEMBL28411099 | 0.88 | KDM4E (0.44) | CREBBPEP300BRD2BRD3EPHB3 | |
| SCHEMBL28410723 | 0.87 | CREBBP (0.45) | CREBBPEP300BRD2BRD3EPHB3 | |
| SCHEMBL28416810 | 0.87 | ABCB1 (0.45) | CREBBPBRD2BRD3 | |
| SCHEMBL28411095 | 0.87 | CREBBP (0.63) | CREBBPEP300BRD2BRD3 | |
| SCHEMBL28416806 | 0.87 | CREBBP (0.59) | CREBBPEP300BRD2BRD3 | |
| SCHEMBL28413319 | 0.87 | CREBBP (0.73) | CREBBPEP300BRD2BRD3CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320621-A | Indolizine compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-06-23 | — | — | CN | disclosed |