Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416810 | 0.90 | ABCB1 (0.45) | KDM4ECREBBPALDH1A1MAPTLMNA | |
| SCHEMBL28417785 | 0.89 | CREBBP (0.44) | CREBBPMAPTHTTPOLBEPHB3 | |
| SCHEMBL28891091 | 0.89 | CREBBP (0.41) | KDM4EGAACREBBPMAPTLMNA | |
| SCHEMBL28415697 | 0.88 | CREBBP (0.58) | CREBBPEPHB3BRD2BRD3EP300 | |
| SCHEMBL28410723 | 0.87 | CREBBP (0.45) | KDM4EGAACREBBPEPHB3TP53 | |
| SCHEMBL28419775 | 0.86 | CREBBP (0.46) | KDM4ECREBBPALDH1A1EPHB3BRD2 | |
| SCHEMBL28422565 | 0.86 | LCLAT1 (0.40) | KDM4ECREBBPALDH1A1MAPTHTT | |
| SCHEMBL28415713 | 0.86 | CREBBP (0.46) | CREBBPHTTPOLBEPHB3RAB9A | |
| SCHEMBL28419951 | 0.85 | SMN1; SMN2 (0.39) | KDM4ECREBBPALDH1A1MAPTHTT | |
| SCHEMBL28418305 | 0.84 | CREBBP (0.43) | CREBBPHTTPOLBEPHB3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320621-A | Indolizine compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-06-23 | — | — | CN | disclosed |