Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.62 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778106 | 0.89 | KDR (0.62) | KDRL3MBTL1GAAGRM4KMT2A | |
| SCHEMBL28434027 | 0.84 | KDR (0.63) | KDRL3MBTL1GAAKMT2ATP53 | |
| SCHEMBL28891850 | 0.84 | KDR (0.63) | KDRL3MBTL1GAAGRM4KMT2A | |
| SCHEMBL23360257 | 0.83 | KMT2A (0.74) | KDRSLC40A1L3MBTL1GAAKMT2A | |
| SCHEMBL29862819 | 0.83 | KMT2A (0.74) | KDRSLC40A1L3MBTL1GAAKMT2A | |
| SCHEMBL17597171 | 0.81 | KDM4E (0.57) | KDRSLC40A1L3MBTL1GAAKMT2A | |
| SCHEMBL6054969 | 0.81 | NPC1 (0.60) | GRM4KMT2ATP53MEN1NPC1 | |
| SCHEMBL31565287 | 0.80 | SLC40A1 (0.52) | KDRSLC40A1L3MBTL1GAAKMT2A | |
| SCHEMBL28510851 | 0.80 | SLC40A1 (0.59) | KDRSLC40A1L3MBTL1GAAKMT2A | |
| SCHEMBL28676976 | 0.80 | KDR (0.58) | KDRL3MBTL1GAAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925685-B | Triheteroaryltertiary amine and synthesis method thereof | 南昌大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-111320579-B | Preparation method of 8-amide-5-halogenated quinoline derivative | 常州工程职业技术学院 | 2021-06-29 | — | — | CN | disclosed |
| CN-111519204-B | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111519204-B | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111519204-B | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111519204-A | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-111519204-A | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-111519204-A | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-111320579-A | Preparation method of 8-amide-5-halogenated quinoline derivative | 常州工程职业技术学院 | 2020-06-23 | — | — | CN | disclosed |