Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.83 |
| ▸ | RAB9A | P51151 | 5/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.78 |
| ▸ | CASP3 | P42574 | 2/20 | 0.78 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.78 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.78 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053299 | 0.98 | NPC1 (0.87) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10997076 | 0.96 | NPC1 (0.92) | NPC1RAB9AKDM4EMAPTMEN1 | |
| Fluoride SCHEMBL27588167 | 0.94 | NPC1 (0.88) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.91 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.91 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL28541064 | 0.90 | NPC1 (0.69) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL6529483 | 0.89 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL11652520 | 0.89 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL28371904 | 0.89 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL29440010 | 0.89 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813523-A | Bisindole biphenyl compound and preparation method and application thereof | 贵州医科大学 | 2023-09-29 | — | — | CN | claimed |
| CN-116813523-A | Bisindole biphenyl compound and preparation method and application thereof | 贵州医科大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-108292708-B | Organic electroluminescent device | 保土谷化学工业株式会社 | 2020-03-03 | — | — | CN | disclosed |