Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.87 |
| ▸ | RAB9A | P51151 | 5/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | CASP3 | P42574 | 2/20 | 0.81 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.81 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.81 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416625 | 0.98 | NPC1 (0.83) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10997076 | 0.94 | NPC1 (0.92) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.93 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.93 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTMEN1 | |
| Fluoride SCHEMBL27588167 | 0.92 | NPC1 (0.88) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL29788796 | 0.91 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL28371904 | 0.91 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL11652520 | 0.91 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL29440010 | 0.91 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL6529483 | 0.91 | NPC1 (0.96) | NPC1RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1340113-A | heat-resistant crimped yarn | TORAY DU PONT KK (JP) | 2002-03-13 | — | — | CN | claimed |
| US-5770121-A | Solid state coagulation of optical quality polymer thin films | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1998-06-23 | — | — | US | claimed |
| US-5492666-A | EXPOSING TO A NONSOVENT VAPOR | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-02-20 | — | — | US | claimed |
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | claimed |
| US-5086120-A | Ionically blended molecular composites | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-02-04 | — | — | US | claimed |
| US-10323338-B2 | Process for making composites comprising rigid-rod polymers and graphene nanoparticles | TJC Polymer Inc. (US) | 2019-06-18 | — | — | US | disclosed |
| US-20180105957-A1 | PROCESS FOR MAKING COMPOSITES COMPRISING RIGID-ROD POLYMERS AND GRAPHENE NANOPARTICLES | DANG THUY D (US) | 2018-04-19 | — | — | US | disclosed |
| US-9850596-B2 | Composites comprising rigid-rod polymers and graphene nanoparticles and process for making the same | TJC Polymer Inc. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | SIMON FRASER UNIVERSITY (CA) | 2017-08-03 | — | — | US | disclosed |
| WO-2016004513-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | SIMON FRASER UNIVERSITY (CA) | 2016-01-14 | — | — | WO | disclosed |
| US-20150218730-A1 | COMPOSITES COMPRISING RIGID-ROD POLYMERS AND GRAPHENE NANOPARTICLES AND PROCESS FOR MAKING THE SAME | DANG THUY D (US) | 2015-08-06 | — | — | US | disclosed |
| EP-1421032-B1 | COMPOSITIONS COMPRISING RIGID-ROD POLYMERS AND CARBON NANOTUBES AND PROCESS FOR MAKING THE SAME | GEORGIA TECH RES INST (US) | 2008-11-19 | — | — | EP | disclosed |
| US-5606638-A | Organic scintillator systems and optical fibers containing polycyclic aromatic compounds | NANOPTICS INCORPORATED (US) | 1997-02-25 | — | — | US | disclosed |
| US-5536866-A | Triarylamine-based dinitrile and dicarboxylic acid monomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-07-16 | — | — | US | disclosed |
| US-5534613-A | ELECTROCONDUCTORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-07-09 | — | — | US | disclosed |
| US-5521277-A | ELECTROCONDUCTIVE POLYMERS WITH POLYTHIAZOLES OR POLYOXAZOLE GROUPS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1996-05-28 | — | — | US | disclosed |
| US-5426173-A | Polybenzoxazoles having improved compressive strength | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1995-06-20 | — | — | US | disclosed |
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| US-5194519-A | Benzobisimidazoles or benzothiazoles in polyether ketone or ether ether ketone polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1993-03-16 | — | — | US | disclosed |
| US-5086120-A | Ionically blended molecular composites | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | PDK1, PDK3, PDK2 | NPC1 2398/4885RAB9A 4231/4885KDM4E 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.