Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419184 | 0.89 | IDO1 (0.40) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL9419180 | 0.89 | IDO1 (0.40) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL23347668 | 0.78 | SLC6A2 (0.40) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL6205167 | 0.74 | PPARG (0.43) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL7417710 | 0.74 | SLC6A2 (0.50) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL6205165 | 0.74 | PPARG (0.43) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL14586288 | 0.73 | TRPA1 (0.44) | SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL6202382 | 0.72 | SLC6A2 (0.41) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL20749211 | 0.71 | SLC6A2 (0.44) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL3088437 | 0.71 | TAAR1 (0.54) | IDO1SLC6A2SLC6A4SLC6A3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138461-B | Continuous preparation method of o-chlorobenzyl chloride Grignard reagent | 海利尔药业集团股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-111138461-A | Continuous preparation method of o-chlorobenzyl chloride Grignard reagent | 海利尔药业集团股份有限公司 | 2020-05-12 | — | — | CN | disclosed |