Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328928 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BSMN1; SMN2HTR2AKDM4E | |
| SCHEMBL24328897 | 0.86 | MTNR1A (0.58) | MTNR1AMTNR1BSMN1; SMN2HTR2AKDM4E | |
| SCHEMBL29982303 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL1461102 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| Benzene SCHEMBL28112748 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL18029023 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL838982 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL24328921 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR2AKDM4EPOLBMAPT | |
| SCHEMBL28417401 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR2AKDM4EPOLBMAPT | |
| SCHEMBL21808835 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BSMN1; SMN2HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111303001-A | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |