Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417399 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BSMN1; SMN2HTR2AKDM4E | |
| SCHEMBL24328897 | 0.86 | MTNR1A (0.58) | MTNR1AMTNR1BSMN1; SMN2HTR2AKDM4E | |
| SCHEMBL29982303 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL1461102 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| Benzene SCHEMBL28112748 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL18029023 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL838982 | 0.85 | KDM4E (0.59) | MTNR1AMTNR1BHTR2AKDM4EALDH1A1 | |
| SCHEMBL24328921 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR2AKDM4EPOLBMAPT | |
| SCHEMBL28417401 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR2AKDM4EPOLBMAPT | |
| SCHEMBL21808835 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BSMN1; SMN2HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | MTNR1A 2266/4885MTNR1B 1790/4885SMN1; SMN2 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.