Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22356812 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL18680576 | 0.85 | SLC1A3 (0.41) | ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL288891 | 0.81 | SHBG (0.57) | ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL28758251 | 0.81 | SHBG (0.57) | ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL27644093 | 0.79 | SHBG (0.54) | ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL27665614 | 0.79 | SLC7A5 (0.42) | ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1 | |
| SCHEMBL5323173 | 0.77 | SLC1A2 (0.38) | ALDH1A1SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL5323179 | 0.77 | SLC1A2 (0.38) | ALDH1A1SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL5520204 | 0.77 | ALDH1A1 (0.52) | ALDH1A1EPHX1SHBGCYP2C19 | |
| SCHEMBL5416686 | 0.76 | ALDH1A1 (0.60) | ALDH1A1EPHX1GRIK1DPP4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372942-A | β -catenin function modulating agents and methods thereof | 弗格制药有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-111372942-A | β -catenin function modulating agents and methods thereof | 弗格制药有限公司 | 2020-07-03 | — | — | CN | disclosed |