SCHEMBL28417828

SCHEMBL28417828

CC=CCOC(=O)/C=C\C(=O)OCC=CC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.43
ATM Q13315 1/20 0.43
MAPT P10636 3/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
GSTP1 P09211 1/20 0.33
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11054119 0.93 GSTP1 (0.39) HCAR2ATMMAPTCACNA1BAPBA1
SCHEMBL2469637 0.91 HCAR2 (0.57) HCAR2ATMMAPTCACNA1BAPBA1
SCHEMBL8672035 0.91 HCAR2 (0.57) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7746005 0.87 MAPT (0.39) HCAR2ATMMAPTCACNA1BAPBA1
SCHEMBL8961867 0.85
SCHEMBL28725778 0.85 GSTP1 (0.40) HCAR2ATMMAPTCACNA1BAPBA1
SCHEMBL20560076 0.84 HCAR2 (0.39) HCAR2ATMMAPTCACNA1BAPBA1
SCHEMBL4893996 0.83 TSHR (0.32) HCAR2ATMMAPTCACNA1BAPBA1
SCHEMBL29035626 0.83 HCAR2 (0.48) HCAR2ATMMAPTCACNA1BAPBA1
Lithium Ion SCHEMBL29035624 0.82 HCAR2 (0.32) HCAR2ATMMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112210208-B Polyamide resin composition and method for producing molded article 旭化成株式会社 2023-07-25 CN claimed
CN-111212731-B Composite material with direct bonding between rubber and foam 陶氏环球技术有限责任公司 2022-06-21 CN claimed
CN-111212731-A Composite material with direct bonding between rubber and foam 性能材料北美股份有限公司 2020-05-29 CN claimed
CN-112210208-B Polyamide resin composition and method for producing molded article 旭化成株式会社 2023-07-25 CN disclosed
CN-111212731-B Composite material with direct bonding between rubber and foam 陶氏环球技术有限责任公司 2022-06-21 CN disclosed
CN-112210208-A Polyamide resin composition and process for producing molded article 旭化成株式会社 2021-01-12 CN disclosed
CN-111212731-A Composite material with direct bonding between rubber and foam 性能材料北美股份有限公司 2020-05-29 CN disclosed