Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417828 | 0.82 | HCAR2 (0.43) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL11054119 | 0.76 | GSTP1 (0.39) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL27801168 | 0.76 | GSTP1 (0.39) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL8672035 | 0.74 | HCAR2 (0.57) | HCAR2ATMMAPT | |
| SCHEMBL2469637 | 0.74 | HCAR2 (0.57) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL27630882 | 0.74 | HCAR2 (0.54) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| Crotonic Acid SCHEMBL29035643 | 0.71 | BBOX1 (0.34) | BBOX1 | |
| SCHEMBL29035626 | 0.71 | HCAR2 (0.48) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL7746005 | 0.71 | MAPT (0.39) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| Ethyl Fumarate SCHEMBL5014709 | 0.70 | HCAR2 (0.61) | HCAR2ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110233289-B | High-voltage additive, electrolyte containing same and battery | 李秀艳 | 2023-06-20 | — | — | CN | disclosed |