Urea

Urea

SCHEMBL2841795

COC(O)OC.NC(N)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
ALDH1A1 P00352 2/20 0.40
OR51E2 Q9H255 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
ALOX15 P16050 2/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL8463099 1.00 LMNA (0.40) LMNAALDH1A1OR51E2TDP1SLC1A3
SCHEMBL588236 0.82
Hydroxyl Radical SCHEMBL6552260 0.78
Urea SCHEMBL48876 0.73
Urea SCHEMBL4300101 0.73 ALDH1A1 (0.60) LMNAALDH1A1OR51E2TDP1SLC1A3
Urea SCHEMBL4625226 0.73 ALDH1A1 (0.60) LMNAALDH1A1OR51E2TDP1SLC1A3
SCHEMBL11613953 0.73 ALDH1A1 (0.33) ALDH1A1SLC1A3SLC1A2SLC1A1
Urea SCHEMBL28723467 0.72 ALDH1A1 (0.46) LMNAALDH1A1OR51E2TDP1SLC1A3
Urea SCHEMBL11778858 0.71 TDP1 (0.35) LMNAALDH1A1OR51E2TDP1SLC1A3
SCHEMBL10431804 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3983268-A RANDOM POLYMER OF ALPHA-OLEFIN AND UNSATURATED ACID, AMIDES BASF AKTIENGESELLSCHAFT (DT) 1976-09-28 US claimed
CN-106397739-B Improved epoxy and amine polymer systems and methods for making the same 瀚森公司 2020-02-14 CN disclosed
EP-2652040-B1 IMPROVED EPOXY SYSTEMS AND AMINE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME HEXION RES BELGIUM SA (BE) 2020-01-08 EP disclosed
EP-2652039-B1 IMPROVED EPOXY SYSTEMS AND AMINE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME HEXION RES BELGIUM SA (BE) 2019-10-30 EP disclosed
EP-2220160-B1 EPOXY-PHENOLIC RESINS CO-DISPERSIONS HEXION RES BELGIUM SA (BE) 2019-02-20 EP disclosed
US-9234077-B2 Epoxy systems and amine polymer systems and methods for making the same HEXION INC. (US) 2016-01-12 US disclosed
US-9234116-B2 Epoxy systems and amine polymer systems and methods for making the same HEXION INC. (US) 2016-01-12 US disclosed
US-20140051784-A1 EPOXY SYSTEMS AND AMINE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME MOMENTIVE SPECIALTY CHEMICALS INC. (US) 2014-02-20 US disclosed
US-20140046001-A1 EPOXY SYSTEMS AND AMINE POLYMER SYSTEMS AND METHODS FOR MAKING THE SAME MOMENTIVE SPECIALTY CHEMICALS INC. (US) 2014-02-13 US disclosed
US-8586704-B2 Epoxy systems and amine polymer systems and methods for making the same MOMENTIVE SPECIALTY CHEMICALS INC. (US) 2013-11-19 US disclosed
US-4176221-A Soluble resinous products of polyepoxide-amine adducts and cyclic dicarboxylic acid anhydrides CELANESE POLYMER SPECIALTIES COMPANY (US) 1979-11-27 US disclosed
US-4141871-A WATER IMMISCIBLE BUTANOL CELANESE POLYMER SPECIALTIES COMPANY (US) 1979-02-27 US disclosed
US-4139510-A POLYEPOXIDE-POLYAMINE REACTED WITH A MONOCARBOXYLIC ACID CELANESE POLYMER SPECIALTIES COMPANY (US) 1979-02-13 US disclosed
US-4137140-A Cathodic electrocoating CELANESE POLYMER SPECIALTIES COMPANY (US) 1979-01-30 US disclosed
US-4134864-A Cathodic electrocoating resin system comprising the reaction product of polyepoxide, a polyamine and a monocarboxylic acid CELANESE POLYMER SPECIALTIES COMPANY (US) 1979-01-16 US disclosed
US-4116900-A Cathodic electrocoating resin system from polyepoxide, polyamine, and monoepoxide CELANESE POLYMER SPECIALTIES COMPANY (US) 1978-09-26 US disclosed
US-4093594-A ADDUCTING A DIHYDRIC PHENOL-EPICHLOROHYDRIN POLYEPOXIDE WITH A POLYAMINE, DISTILLING, FURTHER REACTION WITH A MONO-1,2-EPOXIDE CELANESE POLYMER SPECIALTIES COMPANY (US) 1978-06-06 US disclosed
US-4059550-A Aqueous dispersions of polyhydroxy polyether resins and aminoplast resins CELANESE POLYMER SPECIALTIES COMPANY (US) 1977-11-22 US disclosed
US-4049744-A Process for making powder coatings CELANESE POLYMER SPECIALTIES COMPANY (US) 1977-09-20 US disclosed
US-3983268-A RANDOM POLYMER OF ALPHA-OLEFIN AND UNSATURATED ACID, AMIDES BASF AKTIENGESELLSCHAFT (DT) 1976-09-28 US disclosed