Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423401 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL28415700 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL28415130 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL28412320 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL28412322 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL28415129 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL28414785 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL9636841 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL28588152 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDPMP22 | |
| SCHEMBL28559532 | 0.76 | HSD17B10 (0.58) | KDM4EALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303025-A | N-acetyl fleroxacin propenone derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2020-06-19 | — | — | CN | disclosed |