Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415700 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| SCHEMBL28418043 | 0.89 | KDM4E (0.58) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| SCHEMBL8388222 | 0.82 | KDM4E (0.79) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL48145 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL29377022 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL9745337 | 0.79 | KDM4E (0.98) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL11193870 | 0.79 | KDM4E (0.98) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL9745354 | 0.79 | KDM4E (0.98) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL29114441 | 0.78 | KDM4E (0.96) | KDM4EALDH1A1ADRA2BMAPK1HPGD | |
| Fleroxacin SCHEMBL9745343 | 0.78 | KDM4E (0.80) | KDM4EALDH1A1ADRA2BMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303027-A | Fluroxacin acrylketone derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2020-06-19 | — | — | CN | disclosed |