Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657877 | 0.98 | TSHR (0.40) | TSHRHPGDTHRB | |
| Bromide SCHEMBL20235977 | 0.97 | TSHR (0.39) | TSHRHPGDTHRB | |
| Hydrochloric Acid SCHEMBL5385817 | 0.90 | TSHR (0.43) | TSHRHPGDTHRBMAPTBLM | |
| SCHEMBL27847719 | 0.88 | TSHR (0.44) | TSHRHPGDTHRBMAPTLMNA | |
| Hydrochloric Acid SCHEMBL28658476 | 0.87 | TSHR (0.41) | TSHRHPGDTHRBMAPTBLM | |
| Hydrochloric Acid SCHEMBL7870981 | 0.87 | TSHR (0.41) | TSHRHPGDTHRBMAPTBLM | |
| Hydrochloric Acid SCHEMBL29171399 | 0.87 | TSHR (0.41) | TSHRHPGDTHRBMAPTBLM | |
| Hydrochloric Acid SCHEMBL10684441 | 0.87 | TSHR (0.41) | TSHRHPGDTHRBMAPTBLM | |
| Bromide SCHEMBL27905014 | 0.87 | TSHR (0.43) | TSHRHPGDTHRBMAPTLMNA | |
| Fluoride Ion SCHEMBL28241936 | 0.87 | TSHR (0.43) | TSHRHPGDTHRBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111378070-B | Preparation method and application of fracturing thickening agent | 东营市盛聚化工有限责任公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-111378070-A | Preparation method and application of fracturing thickening agent | 东营市盛聚化工有限责任公司 | 2020-07-07 | — | — | CN | disclosed |