SCHEMBL28419081

SCHEMBL28419081

O=S(=O)(c1ccccc1)C(F)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.39
HSD11B1 P28845 3/20 0.39
APOBEC3G Q9HC16 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA5A P35218 2/20 0.37
CA9 Q16790 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA12 O43570 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37
PLA2G7 Q13093 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28362022 0.74 APOBEC3G (0.37) HTR6HSD11B1APOBEC3GCA1CA2
SCHEMBL719362 0.73 LMNA (0.50) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL1357362 0.73 HTR6 (0.50) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL776342 0.72 HTR6 (0.44) HTR6HSD11B1APOBEC3GCA1CA2
Iodide SCHEMBL31414542 0.72 LMNA (0.49) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL775525 0.70 HTR6 (0.46) HTR6HSD11B1APOBEC3GCA1CA2
SCHEMBL7631040 0.70 HTR6 (0.46) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL776304 0.70 HTR6 (0.46) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL13623396 0.69 HTR6 (0.41) HTR6HSD11B1APOBEC3GCA1CA2
SCHEMBL13623398 0.69 HTR6 (0.41) HTR6HSD11B1APOBEC3GCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234218-A Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2020-06-05 CN claimed
CN-111234218-B Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2022-12-27 CN disclosed
CN-111234218-A Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2020-06-05 CN disclosed