Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 3/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419446 | 1.00 | ACE (0.74) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL111236 | 0.98 | ACE (0.76) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL111235 | 0.98 | ACE (0.76) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL528464 | 0.98 | ACE (0.76) | ACEPTPN1CA2CA1GPR132 | |
| Hydrochloric Acid SCHEMBL10622640 | 0.97 | ACE (0.74) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL4357736 | 0.92 | ACE (0.68) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL4356229 | 0.92 | ACE (0.68) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL2632872 | 0.90 | PTPN1 (0.74) | ACEPTPN1CA2CA1L3MBTL1 | |
| SCHEMBL6857183 | 0.90 | PTPN1 (0.69) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL10033681 | 0.90 | PTPN1 (0.69) | ACEPTPN1CA2CA1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303086-A | Chiral hydroxy lactone amide compound and synthesis method thereof | 温州大学 | 2020-06-19 | — | — | CN | disclosed |