Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413304 | 0.88 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12803743 | 0.86 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28413277 | 0.86 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL418384 | 0.85 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7186268 | 0.84 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28419096 | 0.84 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10505424 | 0.84 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28418521 | 0.84 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1AGTR1 | |
| SCHEMBL28418471 | 0.84 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30554022 | 0.84 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-A | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111187218-A | Application of 1-substituted-1H-imidazole-2-carboxylic acid compounds in preparation of metal β -lactamase inhibitor | 四川大学 | 2020-05-22 | — | — | CN | disclosed |