Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483452 | 0.94 | CA12 (0.50) | CYP3A4TSHRLMNAGABRA1GABRG2 | |
| SCHEMBL16364952 | 0.91 | GABRA1 (0.48) | CYP3A4TSHRLMNAGABRA1GABRG2 | |
| SCHEMBL27994463 | 0.87 | GABRA1 (0.43) | CYP3A4TSHRLMNAGABRA1GABRG2 | |
| Hydrochloric Acid SCHEMBL13386291 | 0.85 | LMNA (0.41) | CYP3A4TSHRLMNAGABRA1GABRG2 | |
| SCHEMBL28414501 | 0.81 | CA12 (0.43) | CYP3A4TSHRCA12CA7CA14 | |
| SCHEMBL18855930 | 0.80 | CA12 (0.56) | CYP3A4TSHRCA12CA7CA14 | |
| SCHEMBL28216318 | 0.79 | LMNA (0.45) | CYP3A4TSHRLMNAGABRA1GABRG2 | |
| SCHEMBL6057631 | 0.78 | CA12 (0.61) | CYP3A4TSHRCA12CA7CA14 | |
| SCHEMBL1048715 | 0.78 | CA12 (0.61) | CYP3A4TSHRCA12CA7CA14 | |
| SCHEMBL11134361 | 0.78 | CA12 (0.61) | CYP3A4TSHRCA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914256-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-03-24 | — | — | CN | disclosed |