Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424469 | 0.93 | MEN1 (0.53) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL28400173 | 0.93 | TUBB4A (0.50) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28420109 | 0.91 | CYP2D6 (0.52) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL28417224 | 0.88 | MEN1 (0.55) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL28405880 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTHTTNMT2 | |
| SCHEMBL28405873 | 0.84 | CYP2D6 (0.52) | MEN1KMT2AKDM4EHTTNMT2 | |
| SCHEMBL28891460 | 0.81 | ADRB2 (0.57) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL28411240 | 0.81 | MEN1 (0.54) | MEN1KMT2AKDM4ELMNAADRB2 | |
| Hydrochloric Acid SCHEMBL28408119 | 0.80 | MEN1 (0.53) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28405963 | 0.80 | ADRB2 (0.53) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107857748-B | 5- [ 2-hydroxy-3- (alkylamino) propoxy ] benzofuran compound and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | claimed |
| CN-107857748-B | 5- [ 2-hydroxy-3- (alkylamino) propoxy ] benzofuran compound and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | disclosed |