Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.57 |
| ▸ | CTSB | P07858 | 18/20 | 0.54 |
| ▸ | CTSS | P25774 | 17/20 | 0.54 |
| ▸ | CTSK | P43235 | 5/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421501 | 0.86 | CTSL (0.59) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL28416332 | 0.85 | CTSL (0.58) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL28425996 | 0.85 | CTSL (0.58) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL6184450 | 0.78 | CTSL (0.72) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL18615860 | 0.76 | CTSL (0.35) | CTSLCTSBCTSSCTSK | |
| SCHEMBL18616539 | 0.76 | CTSL (0.35) | CTSLCTSBCTSSCTSK | |
| SCHEMBL28427138 | 0.76 | CTSL (0.64) | CTSLCTSBCTSSCTSK | |
| SCHEMBL28424711 | 0.76 | CTSL (0.74) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL28421665 | 0.76 | CTSL (0.74) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL18616594 | 0.73 | CTSB (0.43) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928113-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-07-07 | — | — | CN | disclosed |