Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GRK2 | P25098 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353231 | 0.84 | NPC1 (0.54) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 | |
| SCHEMBL24972281 | 0.83 | NPC1 (0.53) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 | |
| SCHEMBL17498094 | 0.80 | NPC1 (0.49) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 | |
| SCHEMBL20560684 | 0.79 | LMNA (0.46) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 | |
| SCHEMBL4796769 | 0.79 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 | |
| SCHEMBL3441761 | 0.76 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 | |
| SCHEMBL19279031 | 0.75 | FGFR1 (0.59) | LMNA | |
| SCHEMBL27625364 | 0.74 | LMNA (0.66) | ALDH1A1L3MBTL1POLBRAB9AMAPT | |
| SCHEMBL7982548 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1L3MBTL1POLBNPC1SMN1; SMN2 | |
| SCHEMBL16045456 | 0.74 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1POLBGRK2CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333513-B | Preparation method of 2,4-difluoro-3-nitrobenzoic acid | 江苏恒沛药物科技有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-111333513-A | Preparation method of 2,4-difluoro-3-nitrobenzoic acid | 江苏恒沛药物科技有限公司 | 2020-06-26 | — | — | CN | disclosed |