Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | ITK | Q08881 | 2/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802382 | 0.88 | ALDH1A1 (0.59) | KMT2AMEN1RAB9AMAPTLMNA | |
| SCHEMBL7968814 | 0.88 | MEN1 (0.79) | KMT2AMEN1POLBRAB9AGAA | |
| SCHEMBL27641820 | 0.87 | GAA (0.70) | KMT2AMEN1RAB9AGAAMAPT | |
| SCHEMBL9427642 | 0.87 | DDX3X (0.65) | KMT2AMEN1POLBNR4A1RAB9A | |
| SCHEMBL9403861 | 0.87 | MEN1 (0.65) | KMT2AMEN1RAB9AMAPTLMNA | |
| SCHEMBL15259150 | 0.87 | HPGD (0.66) | KMT2AMEN1POLBRAB9A | |
| SCHEMBL6692876 | 0.85 | NPC1 (0.57) | KMT2AMEN1POLBRAB9AMAPT | |
| SCHEMBL31444807 | 0.85 | NPC1 (0.57) | KMT2AMEN1POLBRAB9AMAPT | |
| SCHEMBL2781923 | 0.84 | EPHX2 (0.61) | KMT2AMEN1GAAMAPT | |
| SCHEMBL26627751 | 0.84 | MAPT (0.72) | KMT2AMEN1RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333513-B | Preparation method of 2,4-difluoro-3-nitrobenzoic acid | 江苏恒沛药物科技有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-111333513-A | Preparation method of 2,4-difluoro-3-nitrobenzoic acid | 江苏恒沛药物科技有限公司 | 2020-06-26 | — | — | CN | disclosed |