Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30827320 | 0.87 | CA1 (0.54) | POLBSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL11133278 | 0.87 | CA1 (0.54) | POLBSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL11420427 | 0.84 | POLB (0.47) | POLBSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL11315297 | 0.84 | CYP1A2 (0.43) | POLBSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL11432617 | 0.83 | HTT (0.48) | POLBSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL9313406 | 0.81 | POLB (0.56) | POLBSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL11419842 | 0.81 | KMT2A (0.51) | POLBSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL29882963 | 0.76 | POLB (0.51) | POLBSMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL10616266 | 0.75 | CA1 (0.51) | POLBSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL30667032 | 0.74 | ALDH1A1 (0.59) | POLBSMN1; SMN2NPC1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196783-B | 2,4, 6-substituted pyrimidine derivatives containing acyl urea structure, and preparation method and application thereof | 郑州大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-111196783-A | 2,4, 6-substituted pyrimidine derivatives containing acyl urea structure, and preparation method and application thereof | 郑州大学 | 2020-05-26 | — | — | CN | disclosed |