Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 11/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660835 | 0.85 | AHR (0.46) | HTR6HTTAHR | |
| SCHEMBL29829444 | 0.79 | MGLL (0.50) | P2RX4AHRALOX5MGLL | |
| SCHEMBL16604412 | 0.79 | MGLL (0.50) | P2RX4AHRALOX5MGLL | |
| SCHEMBL24893448 | 0.77 | AHR (0.42) | P2RX4AHRALOX5MGLL | |
| SCHEMBL18770825 | 0.76 | POLB (0.52) | HTR6P2RX4 | |
| SCHEMBL30867065 | 0.76 | POLB (0.52) | HTR6P2RX4 | |
| SCHEMBL17127115 | 0.75 | P2RX4 (0.34) | P2RX4 | |
| SCHEMBL17155534 | 0.75 | KDM4E (0.40) | HTTP2RX4 | |
| SCHEMBL20444379 | 0.75 | ALDH1A1 (0.35) | HTR6P2RX4MGLL | |
| SCHEMBL20444380 | 0.73 | POLB (0.42) | HTR6P2RX4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056758-B | Compound with acridine spiroanthrone as core and application thereof in organic electroluminescent device | 中节能万润股份有限公司 | 2020-06-09 | — | — | CN | disclosed |