SCHEMBL28421963

SCHEMBL28421963

[Li]C1(CC(C)c2ccccc2)C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.38
AOC3 Q16853 2/20 0.35
TRPA1 O75762 4/20 0.34
RIPK1 Q13546 1/20 0.34
ADRA2A P08913 1/20 0.30
ADRA2C P18825 1/20 0.30
LMNA P02545 1/20 0.30
HIF1A Q16665 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL29003680 0.98 TAAR1 (0.37) TAAR1AOC3TRPA1RIPK1
SCHEMBL28423844 0.78 TAAR1 (0.31) TAAR1
SCHEMBL17008829 0.74 KDM4E (0.34) KDM4E
SCHEMBL28892013 0.72
Hydrochloric Acid SCHEMBL28891930 0.71 ALDH1A1 (0.31) TAAR1
SCHEMBL29003682 0.71 L3MBTL1 (0.36) LMNAKDM4E
Hydrochloric Acid SCHEMBL29003675 0.70 MEN1 (0.36) LMNAKDM4E
SCHEMBL28420775 0.69 TAAR1 (0.45) TAAR1AOC3TRPA1RIPK1KDM4E
SCHEMBL11809732 0.69 KDM4E (0.33) KDM4E
SCHEMBL22981984 0.69 TAAR1 (0.30) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111406078-B Catalyst for preparing polyethylene with broad bimodal molecular weight distribution 埃克森美孚化学专利公司 2023-03-10 CN disclosed
CN-111406078-A Catalyst for preparing polyethylene with broad bimodal molecular weight distribution 埃克森美孚化学专利公司 2020-07-10 CN disclosed