Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430474 | 0.91 | — | — | |
| SCHEMBL7899169 | 0.72 | HTT (0.44) | HTTALDH1A1TSHRFGFR4 | |
| Sulfuric Acid SCHEMBL23277225 | 0.72 | CA5A (0.32) | HTT | |
| Sulfuric Acid SCHEMBL23277224 | 0.72 | CA5A (0.32) | HTT | |
| SCHEMBL27417808 | 0.72 | HTT (0.44) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL7787905 | 0.70 | — | — | |
| SCHEMBL10608081 | 0.69 | — | — | |
| SCHEMBL175495 | 0.69 | HTT (0.45) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL1640508 | 0.69 | HTT (0.45) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL8668364 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568791-A | Lipase variants and compositions comprising such lipase variants | 诺维信公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-111868239-A | Lipase, lipase variants and compositions thereof | 诺维信公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111356762-A | Lipase variants and microcapsule compositions comprising such lipase variants | 诺维信公司 | 2020-06-30 | — | — | CN | disclosed |