Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837975 | 0.95 | HDAC1 (0.48) | HDAC1HDAC2CYP1A2KDM4COPRM1 | |
| SCHEMBL2842747 | 0.94 | HDAC1 (0.50) | HDAC1HDAC2CYP1A2KDM4COPRM1 | |
| SCHEMBL29858443 | 0.88 | MTNR1A (0.50) | HDAC1HDAC2CYP1A2OPRM1OPRK1 | |
| SCHEMBL19386088 | 0.88 | MTNR1A (0.50) | HDAC1HDAC2CYP1A2OPRM1OPRK1 | |
| SCHEMBL15578063 | 0.81 | HDAC1 (0.61) | HDAC1HDAC2CYP1A2KDM4CCYSLTR1 | |
| SCHEMBL2414395 | 0.79 | PKM (0.47) | HDAC1HDAC2CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL13719339 | 0.78 | SUCNR1 (0.58) | — | |
| Acetic Acid SCHEMBL29172163 | 0.78 | CYP1A2 (0.53) | CYP1A2CYSLTR1CYSLTR2GPBAR1FFAR1 | |
| SCHEMBL9952773 | 0.78 | CYSLTR1 (0.66) | HDAC1HDAC2CYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL29858122 | 0.78 | HTT (0.55) | HDAC1HDAC2CYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251324-A1 | HETEROARYL-ALKYLCARBAMATE COMPOUNDS AND THEIR USE AS INHIBITORS OF THE FAAH ENZYME | Sanofi-Aventis (FR) | 2010-11-17 | — | — | EP | disclosed |
| EP-1720829-B1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-10-14 | — | — | EP | disclosed |