Fleroxacin

Fleroxacin

SCHEMBL48145

CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(CCF)c3c2F)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 1.00
ALDH1A1 P00352 7/20 0.67
ADRA2B P18089 1/20 0.60
MAPK1 P28482 1/20 0.60
HPGD P15428 7/20 0.59
HSD17B10 Q99714 6/20 0.59
DRD3 P35462 1/20 0.58
ALB P02768 1/20 0.57
HRH3 Q9Y5N1 1/20 0.57
TUBB4A P04350 1/20 0.56
POLB P06746 1/20 0.56
TUBB P07437 1/20 0.56
TUBA3C P0DPH7 1/20 0.56
TUBA1B P68363 1/20 0.56
TUBA4A P68366 1/20 0.56
TUBB4B P68371 1/20 0.56
TUBB3 Q13509 1/20 0.56
TUBB2A Q13885 1/20 0.56
TUBB8 Q3ZCM7 1/20 0.56
TUBA3E Q6PEY2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fleroxacin SCHEMBL29377022 1.00 KDM4E (1.00) KDM4EALDH1A1ADRA2BMAPK1HPGD
Fleroxacin SCHEMBL11193870 0.99 KDM4E (0.98) KDM4EALDH1A1ADRA2BMAPK1HPGD
Fleroxacin SCHEMBL9745354 0.99 KDM4E (0.98) KDM4EALDH1A1ADRA2BMAPK1HPGD
Fleroxacin SCHEMBL9745337 0.99 KDM4E (0.98) KDM4EALDH1A1ADRA2BMAPK1HPGD
Fleroxacin SCHEMBL29114441 0.98 KDM4E (0.96) KDM4EALDH1A1ADRA2BMAPK1HPGD
Fleroxacin SCHEMBL27616878 0.94 KDM4E (0.88) KDM4EALDH1A1ADRA2BMAPK1HPGD
Fleroxacin SCHEMBL12095167 0.93 KDM4E (0.86) KDM4EALDH1A1ADRA2BMAPK1HPGD
SCHEMBL21783262 0.92 KDM4E (0.86) KDM4EALDH1A1ADRA2BMAPK1HPGD
SCHEMBL10742754 0.92 KDM4E (0.86) KDM4EALDH1A1ADRA2BMAPK1HPGD
SCHEMBL312186 0.92 KDM4E (0.86) KDM4EALDH1A1ADRA2BMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10845 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
US-20260090584-A1 SYSTEMS AND METHODS FOR ESTIMATING AEROSOLIZATION EMISSION SCIENTIFIC HORIZONS CONSULTING LLC (US) 2026-04-02 US claimed
EP-4659014-A1 EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING President And Fellows Of Harvard College (US) 2025-12-10 EP claimed
EP-4590371-A2 SYSTEMS AND METHODS FOR ESTIMATING AEROSOLIZATION EMISSION Scientific Horizons consulting LLC (US) 2025-07-30 EP claimed
US-20250228841-A1 COMPOSITIONS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES APTORUM THERAPEUTICS LTD (HK) 2025-07-17 US claimed
US-12350281-B2 Long-acting injectable formulations and use thereof DECHRA VETERINARY PRODUCTS, LLC (US) 2025-07-08 US claimed
EP-4571306-A1 STABILIZING OXYGEN IN A COMPOSITION Instrumentation Laboratory Company (US) 2025-06-18 EP claimed
CN-120142412-A Stabilizing oxygen in a composition 仪器实验室公司 2025-06-13 CN claimed
CN-118465149-B Pretreatment method for improving analysis efficiency of various antibiotics in organic fertilizer 生态环境部南京环境科学研究所 2025-06-13 CN claimed
US-20250189479-A1 STABILIZING OXYGEN IN A COMPOSITION INSTRUMENTATION LABORATORY COMPANY 2025-06-12 US claimed
US-5188833-A Antibacterial quinolinecarboxylic acid derivatives; photostability, heat resistance KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-23 US claimed
US-5179096-A Treatment or pneumocystosis pneumonia RHONE-POULENC SANTE (FR) 1993-01-12 US claimed
EP-0322892-B1 FREEZE-DRIED PHARMACEUTICAL PREPARATIONS FOR PARENTERAL USE KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1992-03-25 EP claimed
EP-0470252-A1 ANTI-HIV DRUG DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-02-12 EP claimed
EP-0453952-A2 A process for synthesizing cephalosporin compounds F. HOFFMANN-LA ROCHE AG (CH) 1991-10-30 EP claimed
WO-1991009616-A1 QUINOLONE ANTIBIOTICS ENCAPSULATED IN LIPID VESICLES YALE UNIVERSITY (US) 1991-07-11 WO claimed
EP-0394553-A2 Use of fluorine containing pyridone carboxylic acid derivatives for preparing a medicament for the treatment of HIV infections DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1990-10-31 EP claimed
EP-0322892-A1 Freeze-dried pharmaceutical preparations for parenteral use KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1989-07-05 EP claimed
US-4563485-A SURGICAL IMPLANTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1986-01-07 US claimed
US-4398029-A BACTERICIDES KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1983-08-09 US claimed