Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681217 | 1.00 | MAPT (0.69) | MAPTRAB9ANPC1CA2CA12 | |
| SCHEMBL28423898 | 1.00 | MAPT (0.69) | MAPTRAB9ANPC1CA2CA12 | |
| SCHEMBL30681174 | 1.00 | MAPT (0.69) | MAPTRAB9ANPC1CA2CA12 | |
| SCHEMBL28418793 | 0.88 | NOS1 (0.53) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL28418792 | 0.88 | NOS1 (0.53) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL30681183 | 0.88 | NOS1 (0.53) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL30681166 | 0.88 | NOS1 (0.53) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL28655754 | 0.86 | MAPT (0.58) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL11577315 | 0.85 | MAPT (0.57) | MAPTRAB9ANPC1CA2CA12 | |
| SCHEMBL28422801 | 0.85 | MAPT (0.57) | MAPTRAB9ANPC1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217722-B | Azo aryl urea derivative, and preparation method and application thereof | 华东理工大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-111217722-A | Azo aryl urea derivative and preparation method and application thereof | 华东理工大学 | 2020-06-02 | — | — | CN | disclosed |