SCHEMBL28655754

SCHEMBL28655754

CC(=O)c1cccc(N=Nc2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.58
KMT2A Q03164 8/20 0.58
MEN1 O00255 6/20 0.58
MAPK1 P28482 3/20 0.58
ALDH1A1 P00352 3/20 0.58
TDP1 Q9NUW8 2/20 0.54
TRPA1 O75762 1/20 0.52
RAB9A P51151 6/20 0.49
NPC1 O15118 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
STAT3 P40763 1/20 0.48
STAT1 P42224 1/20 0.48
GFER P55789 1/20 0.48
POLB P06746 2/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28423898 0.86 MAPT (0.69) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL28423902 0.86 MAPT (0.69) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL30681174 0.86 MAPT (0.69) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL30681217 0.86 MAPT (0.69) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL28545671 0.85 KMT2A (0.51) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL5486185 0.84 TRPA1 (0.67) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL14437429 0.84 TRPA1 (0.67) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL28418793 0.84 NOS1 (0.53) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL28418792 0.84 NOS1 (0.53) MAPTKMT2AMEN1MAPK1ALDH1A1
SCHEMBL30681183 0.84 NOS1 (0.53) MAPTKMT2AMEN1MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113773234-A Method for oxidizing hydrazine compound into azo compound 台州学院 2021-12-10 CN disclosed