SCHEMBL28423944

SCHEMBL28423944

Nc1ccc2c(c1)Nc1ccc(N)cc1O2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.45
MAPT P10636 6/20 0.39
KDM4E B2RXH2 5/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 4/20 0.38
HTR2B P41595 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MITF O75030 1/20 0.38
MAPK1 P28482 1/20 0.38
HTR7 P34969 1/20 0.38
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
CA9 Q16790 2/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31348053 0.92 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL8569985 0.92 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL30879514 0.92 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL1448832 0.92 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL38660914 0.92 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL31191626 0.86 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL33373496 0.86 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL31191641 0.86 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL8520270 0.86 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL3782173 0.86 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119588179-B High-temperature-resistant nanofiltration membrane and preparation method thereof 湖南澳维科技股份有限公司 2025-06-17 CN claimed
CN-119588179-A High-temperature-resistant nanofiltration membrane and preparation method thereof 湖南澳维科技股份有限公司 2025-03-11 CN claimed
CN-119588179-B High-temperature-resistant nanofiltration membrane and preparation method thereof 湖南澳维科技股份有限公司 2025-06-17 CN disclosed
CN-119588179-A High-temperature-resistant nanofiltration membrane and preparation method thereof 湖南澳维科技股份有限公司 2025-03-11 CN disclosed
CN-113754606-B Phenoxazine diamine derivative and/or phenothiazine diamine derivative and preparation method thereof 南京工业大学 2024-03-29 CN disclosed
CN-113754606-A Phenoxazinediamine derivatives and/or phenothiazine diamine derivatives and preparation method thereof 南京工业大学 2021-12-07 CN disclosed
CN-111018850-A Diamine containing phenoxazine structure and polymer thereof with antibacterial effect 湖南工业大学 2020-04-17 CN disclosed