SCHEMBL1448832

SCHEMBL1448832

Nc1ccc2c(c1)Oc1cc(N)ccc1N2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
MAPT P10636 9/20 0.44
KDM4E B2RXH2 7/20 0.44
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
ALDH1A1 P00352 5/20 0.44
GAA P10253 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
MITF O75030 1/20 0.38
MAPK1 P28482 1/20 0.38
HTR2B P41595 1/20 0.38
RAB9A P51151 4/20 0.36
NPC1 O15118 3/20 0.36
LMNA P02545 1/20 0.36
GFER P55789 1/20 0.34
CA9 Q16790 2/20 0.34
HPGD P15428 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38660914 1.00 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL30879514 1.00 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL28423944 0.92 ALOX5 (0.45) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL33373496 0.90 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL31191641 0.90 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL8520270 0.90 ALOX5 (0.65) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL8569985 0.81 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL31348053 0.81 ALOX5 (0.46) ALOX5MAPTKDM4EMEN1KMT2A
SCHEMBL11820212 0.80 ALDH1A1 (0.49) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL28424622 0.78 MAPT (0.44) ALOX5MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023013697-A1 MATERIAL FOR METAL PATTERNING, FLUORO COMPOUND, THIN FILM FOR METAL PATTERNING, ORGANIC ELECTROLUMINESCENCE DEVICE, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN 東ソー株式会社 2023-02-09 WO disclosed
WO-2022034916-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2022-02-17 WO disclosed
CN-111018850-A Diamine containing phenoxazine structure and polymer thereof with antibacterial effect 湖南工业大学 2020-04-17 CN disclosed
US-8975012-B2 Multi-layer articles capable of forming color images and methods of forming color images 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-10 US disclosed
US-20130095435-A1 MULTI-LAYER ARTICLES CAPABLE OF FORMING COLOR IMAGES AND METHODS OF FORMING COLOR IMAGES 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-18 US disclosed
US-8411120-B2 Generation of color images 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-02 US disclosed
US-20110063392-A1 GENERATION OF COLOR IMAGES 3M INNOVATIVE PROPERTIES COMPANY 2011-03-17 US disclosed
EP-0667397-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2001-10-04 EP disclosed
EP-0658095-B1 PROCESS FOR DYEING KERATIN-CONTAINING FIBRES CIBA SC HOLDING AG (CH) 2001-08-29 EP disclosed
EP-0667397-A1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1995-08-16 EP disclosed
US-5393615-A Electrode with acridinone or dibenzoxazepinone mediator on surface MILES INC. (US) 1995-02-28 US disclosed
US-3856788-A DYESTUFF AND METHOD OF MAKING AND USING SAME SAAB-SCANIA AKTIEBOLAG (SE) 1974-12-24 US disclosed