Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138068 | 0.89 | PPARA (0.47) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL16167358 | 0.88 | CYP3A4 (0.51) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL16167352 | 0.88 | CYP3A4 (0.51) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL28432983 | 0.87 | ACHE (0.51) | KDM4ESMN1; SMN2ALDH1A1BCHEALOX5 | |
| SCHEMBL6881641 | 0.85 | BCHE (0.52) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL6881643 | 0.85 | BCHE (0.52) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL1711135 | 0.80 | KDM4E (0.66) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL1711133 | 0.80 | KDM4E (0.66) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL23343707 | 0.80 | CYP3A4 (0.56) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA | |
| SCHEMBL716895 | 0.80 | KMT2A (0.60) | KDM4ESMN1; SMN2ALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106526-B | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | 普罗米蒂克医药SMT有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-106999456-B | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis | 里米诺生物科学有限公司 | 2020-07-10 | — | — | CN | disclosed |