Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPOR | P19235 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424635 | 0.87 | KDM4E (0.50) | ACHEKDM4EALDH1A1SMN1; SMN2EPOR | |
| SCHEMBL1244858 | 0.80 | ACHE (0.58) | ACHEKDM4EALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL6792463 | 0.80 | KDM4E (0.46) | ACHEKDM4EALDH1A1SMN1; SMN2EPOR | |
| SCHEMBL6584626 | 0.78 | TLR4 (0.64) | MAOBTLR4TLR2 | |
| SCHEMBL10782553 | 0.78 | ACHE (0.71) | ACHEKDM4EALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL4138068 | 0.77 | PPARA (0.47) | KDM4EALDH1A1SMN1; SMN2ALOX5ALOX5AP | |
| SCHEMBL3616760 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2MAOBBCHE | |
| SCHEMBL3616763 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2MAOBBCHE | |
| SCHEMBL11444965 | 0.76 | ACHE (0.69) | ACHEKDM4EALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL11668732 | 0.76 | CYP1A1 (0.51) | ACHEKDM4EALDH1A1SMN1; SMN2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106526-B | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | 普罗米蒂克医药SMT有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-106999456-B | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis | 里米诺生物科学有限公司 | 2020-07-10 | — | — | CN | disclosed |