Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 9/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | STK10 | O94804 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428839 | 0.90 | KDR (0.52) | EGFREPHA2KDREPHB4LCK | |
| SCHEMBL22394465 | 0.90 | EGFR (0.61) | EGFREPHA2KDREPHB4LCK | |
| Hydrochloric Acid SCHEMBL28384466 | 0.89 | EGFR (0.60) | EGFREPHA2KDREPHB4LCK | |
| SCHEMBL28427303 | 0.87 | EGFR (0.60) | EGFREPHA2KDRHDAC3HDAC4 | |
| SCHEMBL15520192 | 0.87 | HDAC1 (0.63) | EGFREPHA2KDRHDAC1LCK | |
| SCHEMBL15519473 | 0.82 | HDAC1 (0.61) | EGFRKDRHDAC1LCKRET | |
| SCHEMBL15520010 | 0.81 | ENPP1 (0.50) | EGFREPHA2KDREPHB4FLT1 | |
| SCHEMBL5478005 | 0.76 | EGFR (1.00) | EGFRKDREPHB4LCKFLT1 | |
| SCHEMBL22394455 | 0.75 | EGFR (0.66) | EGFRKDREPHB4LCKFLT1 | |
| Hydrochloric Acid SCHEMBL29623261 | 0.75 | EGFR (1.00) | EGFRKDREPHB4LCKFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | disclosed |