Hydrochloric Acid

Hydrochloric Acid

SCHEMBL29623261

COc1cc2ncnc(Nc3ccc(F)cc3)c2cc1OC.Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR known ✓ P00533 19/20 1.00
LCK known ✓ P06239 7/20 0.78
KDR known ✓ P35968 6/20 0.76
RET known ✓ P07949 3/20 0.74
FLT1 known ✓ P17948 1/20 0.74
FLT3 known ✓ P36888 1/20 0.74
ALK known ✓ Q9UM73 1/20 0.74
ERBB2 known ✓ P04626 1/20 0.70
PDGFRB known ✓ P09619 1/20 0.70
FLT4 known ✓ P35916 1/20 0.70
RIPK2 O43353 2/20 0.74
GAK O14976 1/20 0.74
STK10 O94804 1/20 0.74
JAK3 P52333 1/20 0.74
AAK1 Q2M2I8 1/20 0.74
Q6ZSR9 Q6ZSR9 1/20 0.74
SLK Q9H2G2 1/20 0.74
IRAK4 Q9NWZ3 1/20 0.74
RPS6KA6 Q9UK32 1/20 0.74
CLK1 P49759 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5471121 1.00 EGFR (1.00) EGFRLCKKDRRETRIPK2
SCHEMBL5478005 0.99 EGFR (1.00) EGFRLCKKDRRETRIPK2
SCHEMBL15946888 0.90 EGFR (0.83) EGFRLCKKDRRETRIPK2
SCHEMBL31067662 0.89 EGFR (0.82) EGFRKDRAURKAAURKB
SCHEMBL14964757 0.88 EGFR (0.81) EGFRLCKKDRRETRIPK2
SCHEMBL14964688 0.88 EGFR (0.80) EGFRLCKKDRFLT1
SCHEMBL14964683 0.88 EGFR (0.80) EGFRLCKKDRRETRIPK2
Hydrochloric Acid SCHEMBL5473795 0.88 EGFR (0.80) EGFRLCKKDRRETRIPK2
Hydrochloric Acid SCHEMBL5479915 0.88 EGFR (1.00) EGFRLCKKDRRETRIPK2
Hydrochloric Acid SCHEMBL8871198 0.88 EGFR (0.80) EGFRLCKKDRRETRIPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117630934-A Method for realizing high-resolution wide-amplitude imaging based on multi-frequency pulse diversity and DPCA technology 中国矿业大学 2024-03-01 CN claimed
US-20260108292-A1 BREASTFEEDING SYSTEM SCHWARTZ ALAN N (US) 2026-04-23 US disclosed
EP-4713041-A1 AUTO-INJECTOR AND RELATED METHODS OF USE Regeneron Pharmaceuticals, Inc. (US) 2026-03-25 EP disclosed
US-12465415-B2 Female insertion system SCHWARTZ ALAN N (US) 2025-11-11 US disclosed
US-20250262582-A1 FILTRATION MEDIA MAGNERA CORP (US) 2025-08-21 US disclosed
US-12303814-B2 Filtration media MAGNERA CORPORATION (US) 2025-05-20 US disclosed
US-20250152227-A1 FEMALE INSERTION SYSTEM SCHWARTZ ALAN N (US) 2025-05-15 US disclosed
US-20250092139-A1 HUMAN ANTIBODIES TO PD-L1 REGENERON PHARMACEUTICALS, INC. 2025-03-20 US disclosed
US-12232794-B2 Apparatus for effecting feedback of vaginal cavity physiology SCHWARTZ ALAN N (US) 2025-02-25 US disclosed
WO-2024238847-A1 AUTO-INJECTOR AND RELATED METHODS OF USE REGENERON PHARMACEUTICALS, INC. (US) 2024-11-21 WO disclosed
US-20240382677-A1 AUTO-INJECTOR AND RELATED METHODS OF USE REGENERON PHARMACEUTICALS, INC. (US) 2024-11-21 US disclosed
US-20240337051-A1 NONWOVEN FABRICS INCLUDING RECYCLED POLYPROPYLENE FIBERWEB, LLC 2024-10-10 US disclosed
US-20240316361-A1 Human Antibodies To PD-1 REGENERON PHARMACEUTICALS, INC. 2024-09-26 US disclosed
CN-118144424-A Printing control method and device integrating color register error compensation 广州大学 2024-06-07 CN disclosed
CN-117630934-A Method for realizing high-resolution wide-amplitude imaging based on multi-frequency pulse diversity and DPCA technology 中国矿业大学 2024-03-01 CN disclosed
EP-3967710-A1 HUMAN ANTIBODIES TO PD-1 Regeneron Pharmaceuticals, Inc. (US) 2022-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108292-A1 BREASTFEEDING SYSTEM CFTR, PRSS3, GFRA3 EGFR 23/4885LCK 1553/4885KDR 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.