Phenanthridine

Phenanthridine

SCHEMBL28424979

COc1ccc2c(c1)c(N)nc1ccccc12.c1ccc2c(c1)cnc1ccccc12

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
GPR3 P46089 1/20 0.51
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP1B1 Q16678 1/20 0.50
CLK1 P49759 1/20 0.46
ADORA2A P29274 4/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
ADORA3 P0DMS8 2/20 0.46
ADORA1 P30542 2/20 0.46
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
NQO2 P16083 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ACHE P22303 4/20 0.44
APP P05067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12076878 0.89 CYP1A1 (0.56) KDM4ECYP1A1CYP1A2CYP1B1CLK1
SCHEMBL28988465 0.82 KDM4E (0.56) KDM4EGPR3CYP1A2NPC1RAB9A
SCHEMBL11338975 0.82 KDM4E (0.56) KDM4EGPR3CYP1A2NPC1RAB9A
SCHEMBL6615366 0.78 RAB9A (0.51) KDM4EGPR3CYP1A2NPC1RAB9A
SCHEMBL28428950 0.75 CYP1A1 (0.43) KDM4ECYP1A1CYP1A2CYP1B1CLK1
SCHEMBL1006508 0.74 ADORA2A (0.53) KDM4ECYP1A1CYP1A2CYP1B1CLK1
Phenanthridine SCHEMBL27331192 0.73 GPR3 (0.95) KDM4EGPR3CYP1A2NPC1RAB9A
SCHEMBL30659911 0.73 GPR3 (0.61) KDM4EGPR3CYP1A2ADORA2ANPC1
Phenanthridine SCHEMBL8666 0.72 GPR3 (1.00) KDM4EGPR3CYP1A2NPC1RAB9A
Phenanthridine SCHEMBL9106884 0.72 GPR3 (1.00) KDM4EGPR3CYP1A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749425-B Novel tetradentate platinum complexes 通用显示公司 2020-07-14 CN disclosed