Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424057 | 0.86 | EPHX2 (1.00) | EPHX2HSD11B1NAMPTNPC1RAB9A | |
| SCHEMBL30165693 | 0.76 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL28421290 | 0.74 | EPHX2 (1.00) | EPHX2HSD11B1NAMPT | |
| SCHEMBL13602126 | 0.73 | EPHX2 (0.58) | EPHX2HSD11B1RAB9AHTTLMNA | |
| SCHEMBL30165708 | 0.72 | EPHX2 (0.61) | EPHX2NAMPTNPC1RAB9ATP53 | |
| SCHEMBL30165699 | 0.71 | EPHX2 (0.59) | EPHX2HSD11B1ALDH1A1HPGD | |
| SCHEMBL28431225 | 0.67 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL18286169 | 0.67 | SMN1; SMN2 (0.71) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL4105218 | 0.67 | EPHX2 (0.66) | EPHX2HSD11B1LMNA | |
| SCHEMBL31054288 | 0.66 | HPGD (0.68) | EPHX2NAMPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423396-B | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2023-01-06 | — | — | CN | claimed |
| CN-111423396-A | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | claimed |
| CN-111423396-B | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-111423396-A | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | disclosed |