Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.61 |
| ▸ | NAMPT | P43490 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424057 | 0.73 | EPHX2 (1.00) | EPHX2NAMPTNPC1RAB9ATP53 | |
| SCHEMBL28425569 | 0.72 | EPHX2 (1.00) | EPHX2NAMPTNPC1RAB9AS1PR2 | |
| SCHEMBL30165693 | 0.72 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL20379204 | 0.72 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20379395 | 0.71 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3937889 | 0.69 | EPHX2 (0.83) | EPHX2 | |
| SCHEMBL163309 | 0.69 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15722396 | 0.69 | TGM2 (0.69) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL13674664 | 0.69 | NAMPT (0.51) | EPHX2NAMPTLMNATP53HTT | |
| SCHEMBL28431225 | 0.68 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423396-B | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2023-01-06 | — | — | CN | disclosed |