Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165688 | 0.75 | EPHX2 (0.62) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL4117347 | 0.74 | EPHX2 (0.81) | EPHX2 | |
| SCHEMBL4112779 | 0.74 | EPHX2 (1.00) | EPHX2ALDH1A1 | |
| SCHEMBL1675970 | 0.72 | HSD11B1 (0.57) | EPHX2HSD11B1 | |
| SCHEMBL16530082 | 0.72 | HSD11B1 (0.57) | EPHX2HSD11B1 | |
| SCHEMBL14261033 | 0.72 | HSD11B1 (0.56) | EPHX2HSD11B1 | |
| SCHEMBL4101592 | 0.71 | EPHX2 (0.79) | EPHX2HIF1AEPAS1ALDH1A1MAPT | |
| SCHEMBL28425569 | 0.71 | EPHX2 (1.00) | EPHX2HSD11B1ALDH1A1HPGD | |
| SCHEMBL16940730 | 0.71 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL16666616 | 0.71 | HSD11B1 (0.77) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423396-B | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2023-01-06 | — | — | CN | claimed |
| CN-111423396-B | sEH inhibitor, and preparation method and application thereof | 沈阳药科大学 | 2023-01-06 | — | — | CN | disclosed |