Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144075 | 0.84 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1GAAATM | |
| SCHEMBL31124900 | 0.84 | EPHX2 (0.46) | EPHX2TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL27668592 | 0.83 | TPSAB1 (0.42) | TPSAB1TPSD1TPSG1GAAATM | |
| SCHEMBL29144108 | 0.83 | KMT2A (0.50) | TPSAB1TPSD1TPSG1ATMALDH1A1 | |
| SCHEMBL29179866 | 0.82 | ALDH1A1 (0.55) | TPSAB1TPSD1TPSG1GAAATM | |
| SCHEMBL29260222 | 0.81 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1ATMALDH1A1 | |
| SCHEMBL29143913 | 0.80 | POLB (0.46) | TPSAB1TPSD1TPSG1ALDH1A1GNAI3 | |
| SCHEMBL27668729 | 0.80 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1GAAATM | |
| SCHEMBL10305114 | 0.79 | EPHX2 (0.49) | EPHX2ALDH1A1EPHX1NPC1CHRNB2 | |
| SCHEMBL7295825 | 0.79 | ATM (0.44) | EPHX2GAAATMEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689929-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2024-05-31 | — | — | CN | disclosed |
| CN-117412959-A | Substituted 1-aryl-1 '-heteroaryl compounds, substituted 1,1' -biaryl compounds, and methods of use thereof | 爱彼特生物制药公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-112888674-B | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-112888674-A | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-111689929-A | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-09-22 | — | — | CN | disclosed |
| CN-106659700-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-07-10 | — | — | CN | disclosed |