Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17652250 | 0.84 | CYP1A2 (0.63) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL3433286 | 0.82 | CYP1A2 (0.61) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL1209954 | 0.81 | CYP1A2 (0.51) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL2783408 | 0.81 | CYP1A2 (0.59) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL27285116 | 0.81 | CYP1A2 (0.59) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL1478915 | 0.77 | CYP1A2 (1.00) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL13256158 | 0.76 | CYP1A2 (0.77) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL109583 | 0.76 | CYP1A2 (0.82) | CYP1A2MAPTGAAKMT2AKDM4E | |
| SCHEMBL28230577 | 0.76 | KDM4E (0.66) | KMT2AKDM4ETSHRMEN1 | |
| SCHEMBL30253505 | 0.75 | KDM4E (0.64) | CYP1A2MAPTGAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | claimed |
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |