Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.62 |
| ▸ | IL6 | P05231 | 4/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675790 | 0.89 | TLR7 (0.60) | TLR7 | |
| SCHEMBL28477000 | 0.87 | TLR7 (0.61) | TLR7IL6 | |
| SCHEMBL28426046 | 0.87 | TLR7 (0.62) | TLR7IL6 | |
| SCHEMBL28417397 | 0.85 | TLR7 (0.59) | TLR7IL6 | |
| SCHEMBL28424659 | 0.84 | TLR7 (0.63) | TLR7 | |
| SCHEMBL28422647 | 0.84 | TLR7 (0.63) | TLR7 | |
| SCHEMBL28428260 | 0.84 | TLR7 (0.64) | TLR7 | |
| SCHEMBL28420561 | 0.77 | TLR7 (0.38) | TLR7IL6 | |
| Propane SCHEMBL28428147 | 0.77 | TLR7 (0.62) | TLR7IL6ADORA1 | |
| SCHEMBL18207571 | 0.77 | TLR7 (0.65) | TLR7IL6ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580596-B | Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-07-14 | — | — | CN | disclosed |