SCHEMBL28428281

SCHEMBL28428281

Clc1c(Br)cc(C2CCCc3ccccc32)cc1Br

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GID4 Q8IVV7 1/20 0.51
CYP2D6 P10635 6/20 0.43
ADRA2A P08913 2/20 0.43
ADRA1A P35348 2/20 0.43
ADRA1D P25100 1/20 0.43
ADRA1B P35368 1/20 0.43
HTR1A P08908 1/20 0.43
OPRM1 P35372 1/20 0.43
IGF1R P08069 1/20 0.43
ALOX15 P16050 1/20 0.43
HAO1 Q9UJM8 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
MAPK1 P28482 1/20 0.42
MAPK14 Q16539 1/20 0.42
IDO1 P14902 2/20 0.41
TAS1R3 Q7RTX0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30505550 1.00 GID4 (0.51) GID4CYP2D6ADRA2AADRA1AADRA1D
SCHEMBL20863599 0.78 HAO1 (0.53) GID4ADRA2AADRA1AADRA1DADRA1B
SCHEMBL20863578 0.78 HAO1 (0.53) GID4CYP2D6ADRA2AADRA1AADRA1D
SCHEMBL7075150 0.77 GID4 (0.63) GID4CYP2D6ADRA2AADRA1AADRA1D
SCHEMBL4732235 0.77 SLC6A2 (0.57) GID4CYP2D6ADRA2AADRA1AHTR1A
SCHEMBL5029704 0.77 SLC6A2 (0.57) GID4CYP2D6ADRA2AADRA1AHTR1A
SCHEMBL29757864 0.77 SLC6A2 (0.57) GID4CYP2D6ADRA2AADRA1AHTR1A
SCHEMBL8238524 0.77 SLC6A2 (0.57) GID4CYP2D6ADRA2AADRA1AHTR1A
SCHEMBL395087 0.77 GID4 (0.62) GID4CYP2D6ADRA2AADRA1AADRA1D
SCHEMBL29842306 0.77 GID4 (0.62) GID4CYP2D6ADRA2AADRA1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111372938-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2023-08-08 CN disclosed
CN-111372938-A Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2020-07-03 CN disclosed