Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893714 | 0.84 | KMT2A (0.49) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL4604605 | 0.81 | MAPT (0.68) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL30608270 | 0.79 | NPC1 (0.66) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL429754 | 0.79 | MAPT (1.00) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL6382634 | 0.79 | ALDH1A1 (0.53) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL18702897 | 0.79 | CA12 (0.47) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL11492748 | 0.77 | MAPT (0.62) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL28250973 | 0.76 | MAPT (0.60) | MAPTNPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27716370 | 0.74 | PTPN1 (0.66) | MAPTNPC1KMT2ASMN1; SMN2AHR | |
| SCHEMBL11579032 | 0.74 | MAPT (0.63) | MAPTNPC1KMT2ASMN1; SMN2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111420062-A | Synergistic agent for benzodiazepine drugs | 漳州卫生职业学院 | 2020-07-17 | — | — | CN | claimed |
| CN-115068437-B | Preparation method of benzbromarone capsules | 昆山龙灯瑞迪制药有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115068437-A | Preparation method of benzbromarone capsule | 昆山龙灯瑞迪制药有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111533718-B | Method for preparing benzbromarone | 浙江海洲制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114259485-A | Application of benzbromarone in resisting staphylococcus aureus and biofilm infection thereof | 华中科技大学协和深圳医院 | 2022-04-01 | — | — | CN | disclosed |
| CN-111533718-A | Method for preparing benzbromarone | 浙江海洲制药有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111420062-A | Synergistic agent for benzodiazepine drugs | 漳州卫生职业学院 | 2020-07-17 | — | — | CN | disclosed |
| CN-111420062-A | Synergistic agent for benzodiazepine drugs | 漳州卫生职业学院 | 2020-07-17 | — | — | CN | disclosed |