Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222010 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL128236 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| Water SCHEMBL10990733 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL151444 | 0.86 | ALDH1A1 (0.70) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL1563586 | 0.86 | ALDH1A1 (0.70) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| Water SCHEMBL28428803 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5873323 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL890392 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL2289285 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL9550121 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295195-A | Bacterial and cellular compositions for treating colorectal cancer and methods for assessing prognosis of colorectal cancer patients | 古斯达威罗斯研究所 | 2020-06-16 | — | — | CN | disclosed |