SCHEMBL28429026

SCHEMBL28429026

Cc1ccccc1OCC(N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 2/20 0.61
KDM4E B2RXH2 1/20 0.54
CYP1A2 P05177 1/20 0.54
ALOX15 P16050 1/20 0.54
SLC1A5 Q15758 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
RXRG P48443 1/20 0.49
NOTUM Q6P988 1/20 0.49
KMT2A Q03164 2/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
ADRB2 P07550 1/20 0.48
ADRB1 P08588 1/20 0.48
ADRB3 P13945 1/20 0.48
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28429023 1.00 SCN4A (0.61) SCN4AKDM4ECYP1A2ALOX15SLC1A5
SCHEMBL28437613 1.00 SCN4A (0.61) SCN4AKDM4ECYP1A2ALOX15SLC1A5
SCHEMBL5079199 0.84 TDP1 (0.55) SCN4AKDM4ESLC1A5RXRARXRB
SCHEMBL5079201 0.84 TDP1 (0.55) SCN4AKDM4ESLC1A5RXRARXRB
SCHEMBL10791209 0.84 SCN4A (0.54) SCN4AKDM4ECYP1A2ALOX15NOTUM
SCHEMBL28439054 0.83 LMNA (0.59) KDM4ECYP1A2SLC1A5RXRAKMT2A
SCHEMBL28430552 0.83 LMNA (0.59) KDM4ECYP1A2SLC1A5RXRAKMT2A
SCHEMBL28430550 0.83 LMNA (0.59) KDM4ECYP1A2SLC1A5RXRAKMT2A
SCHEMBL11796071 0.82 SLC1A5 (0.48) KDM4ESLC1A5ADRB2ADRB1ADRB3
SCHEMBL23973559 0.81 KDM4E (0.60) SCN4AKDM4ECYP1A2ALOX15RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333528-B Synthesis method of multi-configuration O-phenyl-serine compound 苏州爱玛特生物科技有限公司 2022-10-21 CN disclosed
CN-111333528-A Synthesis method of multi-configuration O-phenyl-serine compound 苏州爱玛特生物科技有限公司 2020-06-26 CN disclosed