SCHEMBL28430552

SCHEMBL28430552

COc1ccccc1OCC(N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
CYP1A2 P05177 2/20 0.59
KDM4E B2RXH2 1/20 0.59
POLB P06746 1/20 0.57
AGTR1 P30556 1/20 0.54
KMT2A Q03164 1/20 0.51
GRIK1 P39086 1/20 0.49
GRIK2 Q13002 1/20 0.49
GRIK3 Q13003 1/20 0.49
SLC1A5 Q15758 1/20 0.49
RXRA P19793 1/20 0.49
KIF11 P52732 1/20 0.48
ATM Q13315 1/20 0.48
HSD17B10 Q99714 1/20 0.47
MAPT P10636 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
IDO1 P14902 1/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28439054 1.00 LMNA (0.59) LMNASMN1; SMN2CYP1A2KDM4EPOLB
SCHEMBL28430550 1.00 LMNA (0.59) LMNASMN1; SMN2CYP1A2KDM4EPOLB
SCHEMBL28437613 0.83 SCN4A (0.61) LMNASMN1; SMN2CYP1A2KDM4EKMT2A
SCHEMBL28429023 0.83 SCN4A (0.61) LMNASMN1; SMN2CYP1A2KDM4EKMT2A
SCHEMBL28429026 0.83 SCN4A (0.61) LMNASMN1; SMN2CYP1A2KDM4EKMT2A
SCHEMBL11796071 0.82 SLC1A5 (0.48) KDM4ESLC1A5MAPTL3MBTL1
SCHEMBL10441692 0.81 L3MBTL1 (0.52) LMNASMN1; SMN2KDM4EPOLBKMT2A
SCHEMBL5076009 0.81 LMNA (0.60) LMNASMN1; SMN2CYP1A2KDM4EPOLB
SCHEMBL22737054 0.81 KYNU (0.47) LMNACYP1A2KDM4ESLC1A5KIF11
SCHEMBL10441691 0.80 ACHE (0.43) LMNASMN1; SMN2CYP1A2KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333528-B Synthesis method of multi-configuration O-phenyl-serine compound 苏州爱玛特生物科技有限公司 2022-10-21 CN disclosed
CN-111333528-A Synthesis method of multi-configuration O-phenyl-serine compound 苏州爱玛特生物科技有限公司 2020-06-26 CN disclosed